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College of Engineering and Computing

Faculty and Staff

Elizabeth A. Regan

Title: Department Chair and Associate Professor
Department: Integrated Information Technology
College of Engineering and Computing
Phone: 803-777-2286
Fax: 803-777-9564

Innovation Center
550 Assembly Street, Suite 1300
Office 1310
Columbia, SC 29208

Elizabeth A. Regan


Ph.D., University of Connecticut
M.A., B.S., A.S., University of Connecticut

Dr. Elizabeth Regan is chair of the Department of Integrated Information Technology and associate professor of Health Information Technology at the University of South Carolina. She is also an adjunct professor in the Arnold School of Public Health. Prior to joining USC in July 2011, she served as chair of the Department of Information Systems, College of Business, at Morehead State University, Kentucky, for 11 years, and as the Elmer and Donna Smith Endowed Chair in Health Systems Management for two years. She serves on the Board of Directors for the Northeast Kentucky Regional Health Information Organization (NeKY RHIO), of which she is a founding member and first board chair. The RHIO also serves as the Regional Extension Center for Eastern Kentucky. Dr. Regan served five years on the Coordinating Council for the Kentucky State Health Information Exchange and on the faculty of the University of Kentucky Medical School Rural Physician Leadership program. She was recently appointed to the national HIMSS Innovation Committee.

Dr. Regan holds a Ph.D. from the University of Connecticut and previously held appointments as an adjunct professor at New York University and the University of Connecticut School of Business. She brings to the classroom 16 years of IT management experience in industry, where she was responsible for many projects involving system design and implementation, end-user computing, knowledge management, and organizational transformation. Current research interests are primarily in the areas of health information technology and exchange and in information technology, innovation and organizational change. Her projects have been supported by major grants from HRSA, The Office of the National Coordinator for Health Information Technology, the Center for Medicaid and Medicare Innovation Grant, and the U.S. Department of Education. She is the lead author on two college texts on end-user information systems and has published and presented her research in numerous national and international forums.


Health information technology and exchange
Strategic information systems
Large-scale organizational change
Technology innovation and business process redesign (reengineering)
E-commerce and e-business
End-user information systems
Knowledge management

Honors and awards

  • Delta Pi Epsilon, Alpha Chapter "Best Book of 2002" Award for End-User Information Systems: Implementing Individual and Workgroup Technologies. (Prentice Hall, 2002).
  • Best Paper Award. Reengineering for Emerging Technologies, Proceedings of the 14th Annual OSRA Research Conference, March 10 –12, 1995, Las Vegas, Nev.
  • Delta Pi Epsilon, Alpha Chapter "Best Book of 1994" Award for End-user Information Systems: Perspectives for Managers and Information Systems Professionals (Prentice Hall, 1994).
  • Listed in Who's Who Among American Women, Who's Who in the Computer Industry, and Who's Who Among International Women
  • Delta Pi Epsilon National Research Award for Doctoral Dissertation, 1983.
  • Graduated with highest honors from University of Connecticut (3.9 out of 4.0)
  • Graduated summa cum laude from Green Mountain College; Gold Medal Award and Distinction in French and Business
  • Outstanding Young Women of America
  • National Business Education Association Award of Merit in Business Education (1971)


  • ITEC 776 Health Information and CLinical Transformation
  • ITEC 747 Management of Health Information Systems


Regan, E.A., and O'Connor, B. N. (2002). End-User Information Systems: Implementing Individual and Work Group Technologies, 2nd Edition. Upper Saddle River, N.J: Prentice Hall, 2002. New York University. 

Regan, E.A., and O'Connor, B. N. (1994). End-user Information Systems: Perspectives for Managers and Systems Professionals, Macmillan Publishing Co.

Regan, E.A., and O'Connor, B. N. (1989). Automating the Office: Office Systems and End‑User Computing, Macmillan Publishing Co.


Regan, E. and Wang, J. (2016) Realizing the Value of EHR Systems: Critical Success Factors, International Journal of Healthcare Information Systems and Informatics, 11:3, p1-18.

Regan, E. and Wang, J. (2015, Winter). "Meaningful use of IT to transform healthcare: What differentiates success from failure?" Journal of Healthcare Information Management (JHIM), vol. 20, no. 1, pp 52-61.

Regan, E. A., and Wymer, S. (2009). "Influential factors in the adoption and use of e-business and e-commerce technologies (EEIT) by small and medium businesses." Journal of Electronic Commerce in Organizations (JECO), Hershey, Pa: IGI Global.

Regan, E. A. (2007). "Knowledge management: Evolving concept and practice." International Journal of Knowledge, Culture, and Change Management, vol. 6,, ISSN1447-9524 print, 1447-9575 online.

Regan, E. A., and Wymer, S. (2006). "Factors influencing e-commerce use in small and medium businesses." Journal of Electronic Markets, vol.15, no.2 (an international refereed journal published by the Institute for Media and Communications Management, University of St. Gallen, Switzerland).

Regan, E. A., Hunt, S., and Kelley, G. (2004). "Implementation of a network print management system: Lessons learned." Annals of Cases on Information Technology (ACIT) (an international refereed journal of IT teaching cases), vol. 6.

Conference Proceedings

Regan, E. (2017) Healthcare Transformation: Impact on CEO Leadership. Fifth Annual Workshop on the Changing Nature of Work (CNoW), International Conference on Information Systems (ICIS 2017), Seoul, South Korea, December 2017. Accepted.

Regan, E. and Agha, A. (2017) Role of Executive Leadership in Healthcare Innovation. 23rd Americas Conference on Information Systems (AMCIS 2017), A Traditional of Innovation, Boston, August 9-13, 2017.

Regan, E. and Agha, A (2016) Impact of Health Information Technology: Critical Role of Executive Leadership in Healthcare Transformation, SIG Health Pre-Conference Workshop, International Conference on Information Systems (ICIS 2016), Dublin, Ireland.

Regan, E. and Wang, J.  (2015) Realizing the Value of EHR Systems: Critical Success Factors. Transactions of the Third International Conference on Health Information Technology Advancement (ICHITA 2015), October 30-31, 2015, Stryker School of Medicine, Western Michigan University, Kalamazoo, MI.  Best Conference Paper Award

Professional service


  • Chair, Board of Directors, Northeast Kentucky Regional Health Information Organization (NeKY RHIO)
  • Kentucky Healthcare Infrastructure Authority (KHIA)
  • Member, HealthBridge Community Partners, collaboration of regional health information exchanges
  • Kentucky e-Health Network Board Advisory Group – responsible for developing the Kentucky e-Health Network Action Plan approved and submitted to the Governor and legislature in 2007.
  • Chair, Steering Committee, Northeast Kentucky Regional Health Information Organization (NEKY-RHIO) (2006-2008)


  • President, SIG-OSRA, A special interest group of the Association of Information Systems (AIS).
  • Vice President, Membership, Organizational Systems Research Association Executive Board, July 1, 2006-2008.
  • Editorial Board for the Information Technology, Training, and Performance Journal, published by the Organizational Systems Research Association. Reviewed 15 manuscripts to date.
  • Editorial Board for the Journal of Business and Training Education
  • National Conference Chair for the 19th Annual OSRA Research Conference, Toronto, Canada, February 2000.
  • Reviewed book manuscript, Harvesting Experience – Reaping the Benefits of Knowledge by Jan Duffy to be published by ARMA International.
  • Research Session Chair, Delta Pi Epsilon Research Conference, Louisville, KY, November 19-21 1998.
  • OSRA Curriculum Model for Organizational & End-User Information Systems, published 1996.
  • Served on OSRA Curriculum Revision Group. Invited to write lead article for Special Curriculum Issue of the OSRA Research Journal, Organizational and End-user Information Systems: Defining the Field, 14:1, Spring, 1996.
  • Principle Investigator for OSRA Research Project: Office Information Systems as a Field of Study and Research. Published in a special issue of the OSRA Research Journal, Bring Office Information Systems into Focus, (11:2), Winter 1993.
  • Board of Directors: Organizational Systems Research Association (OSRA).
  • Served as President (2 terms 1996-7 and 1993-4), Executive Vice-President (1992-3), and Conference Chair (3 terms 1987, 1988, 2000).

Professional affiliations

Health Information and Management Systems Society (HIMSS)
Association of Information Systems (AIS); SIG-OSRA President; AMCIS Conference Track Chair 2008, 2009, 2010.
ACM, Association for Computing Machinery
Decision Sciences Institute
National Business Education Association



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