Healthy Living

Physical Activity and Weight Loss to Improve Function and Pain After Total Knee Replacement (PI: Christine Pellegrini, Ph.D.; Co-Is: Brian Burnikel, MD., Brian Chen, JD, Ph.D., Elizabeth Regan, Ph.D., Gabrielle Turner-McGrievy, Ph.D., Philip Wessinger, Sara Wilcox, Ph.D.)

Funded by the National Institute of Aging (NIA) - R01AG070004 (7/15/2021 - 6/30/2026)

The purpose of this project is to evaluate the effectiveness of the PACE weight loss program in adults after TKR in a fully-powered two-arm randomized controlled trial.

DREAM

Examination of the Dose Response Relationship Between Physical Activity and Arthritis -Attributable Outcomes (PI: Christine Pellegrini, Ph.D.; Co-Is: Sara Wilco, Ph.D., Chih-Hsiang Yang, Ph.D.)

Funded by the Centers for Disease Control and Prevention (CDC) - U48DP006850 - SIP 24-009 (9/30/24-9/29/29)

The purpose of this project is to evaluate the effectiveness of three different doses (45 minutes, 90 minutes, 150 minutes per week) of physical activity for management of arthritis symptoms. 

MOST Energized!

Optimizing a Remote-based Physical Activity Intervention for Adults with Total Knee Replacement (PI: Christine Pellegrini, Ph.D.; MPI: Jessica Unick, Ph.D.; Co-I: Donna Coffman, Ph.D.)

Funded by the National Institute of Aging (NIA) - R01AG088083 (8/15/24-7/31/29)

The purpose of this project is to identify what supplemental intervention components contribute to the greatest increases in physical activity in adults with knee replacement and how the supplemental components + the core Energize! Exercise Program intervention affect pain, physical function, and other targeted mechanisms for physical activity change.